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AdvoGraft™

Single-layer and dual-layer allografts for advanced wound care.
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Single-layer amniotic allograft

for advanced wound care

AdvoGraft One™ is a dehydrated, single-layer amniotic membrane allograft derived from human placental tissue. Designed for use in both acute and chronic wound settings, AdvoGraft One offers a sterile, immune-privileged matrix rich in native extracellular proteins and growth factors. It supports wound healing by promoting epithelialization and reducing inflammation, without requiring cryopreservation or reconstitution.
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AdvoGraft One Sizes

  • 1 x 1 cm (AVO-0101)
  • 2 x 3 cm (AVO-0203)
  • 4 x 4 cm (AVO-0404)
  • 4 x 8 cm (AVO-0408)
  • 2 x 2 cm (AVO-0202)
  • 2 x 4 cm (AVO-0204)
  • 4 x 6 cm (AVO-0406)
  • 10 x 15 cm (AVO-1015)
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AdvoGraft Membrane Dual Sizes

  • 2 x 2 cm (AVD-0202)
  • 2 x 4 cm (AVD-0204)
  • 4 x 6 cm (AVD-0406)
  • 2 x 3 cm (AVD-0203)
  • 4 x 4 cm (AVD-0404)
  • 4 x 8 cm (AVD-0408)
  • 10 x 15 cm (AVD-1015)

Dual-layer amniotic/chorionic

allograft for complex wounds

AdvoGraft Membrane Dual is a dehydrated, dual-layer placental allograft engineered to provide structural integrity and robust biologic activity for the treatment of deep or complex wounds. The graft combines amniotic and chorionic membranes to enhance scaffold durability and optimize cell signaling for tissue regeneration. Packaged sterile and ambient stable, it offers clinical convenience across care settings.

Why choose AdvoGraft?

Biologic performance with operational efficiency

Combines regenerative impact with simple handling and storage protocols.

Reimbursement & practice alignment

Our specialists assist with coding, documentation and integration into clinical workflows for efficient reimbursement.​

Integrated product support

Backed by NHMS’s full-service biologics team for onboarding, application protocols and clinical training.​

Part of a complete biologics portfolio

Use AdvoGraft alongside skin substitutes like Xcell Amnio Matrix™, Xcellerate® and Amnio-MAXX® to tailor treatment plans.

Key product features

Preserves Native Growth Factors

Supports re-epithelialization and modulates chronic inflammation.

Sterile, Shelf-Stable Format

Sterile and shelf-stable (15–30°C); no refrigeration or rehydration required. E-beam sterilized to SAL 10-6

Protects Critical Healing

Preserves ECM architecture and cytokines essential to healing

Flexible Handling & Conformability

Designed for easy manipulation and anatomical contouring without tearing or curling.

Multiple Sizes for Custom Fit

Available in a variety of dimensions to support wounds of different depths and locations.

Easy Storage

No thawing or reconstitution needed.

Clinical Applications

AdvoGraft is indicated for a wide range of chronic and acute wound types, including:

AdvoGraft One

  • Diabetic foot ulcers (DFUs)
  • Venous leg ulcers (VLUs)
  • Pressure injuries
  • Post-surgical wound dehiscence
  • Trauma skin loss
  • Dermal defects

AdvoGraft Membrane Dual

  • Full-thickness ulcers and exposed wound beds
  • Dehisced surgical sites
  • Orthopedic or podiatric wound management
  • Complex trauma wounds requiring biologic support
  • Dermal defects

Ordering Information

Product Code Product Name Size Units UPC
AdvoGraft One
AVO – 0202AdvoGraft One Single-Layer Amniotic Allograft2cm x 2cm400810167295481
AVO – 0203AdvoGraft One Single-Layer Amniotic Allograft2cm x 3cm600810167295498
AVO – 0204AdvoGraft One Single-Layer Amniotic Allograft2cm x 4cm800810167295504
AVO – 0404AdvoGraft One Single-Layer Amniotic Allograft4cm x 4cm1600810167295511
AVO – 0406AdvoGraft One Single-Layer Amniotic Allograft4cm x 6cm2400810167295528
AVO – 0408AdvoGraft One Single-Layer Amniotic Allograft4cm x 8cm3200810167295535
AVO – 1015AdvoGraft One Single-Layer Amniotic Allograft10cm x 15cm15000810167295542
AdvoGraft Membrane Dual
AVD – 0202AdvoGraft Membrane Dual-Layer Allograft2cm x 2cm400810167295559
AVD – 0203AdvoGraft Membrane Dual-Layer Allograft2cm x 3cm600810167295566
AVD – 0204AdvoGraft Membrane Dual-Layer Allograft2cm x 4cm800810167295573
AVD – 0404AdvoGraft Membrane Dual-Layer Allograft4cm x 4cm1600810167295580
AVD – 0406AdvoGraft Membrane Dual-Layer Allograft4cm x 6cm2400810167295597
AVD – 0408AdvoGraft Membrane Dual-Layer Allograft4cm x 8cm3200810167295603
AVD – 1015AdvoGraft Membrane Dual-Layer Allograft10cm x 15cm15000810167295610

Ready to make AdvoGraft part of your wound care strategy?

ThermoTek manufacturers a variety of single-patient use therapy wraps exclusively for use with the VascuTherm therapy device. Our wraps are latex-free and provide a precise comfortable fit.

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Contact Our Biologics Team

Everything you need to know about our medical products

What types of medical supplies do you offer?
We specialize in high-quality medical products including skin substitutes, wound care supplies, red light therapy units, cold therapy systems like ThermoTek’s VascuTherm 5, DME equipment, and more. All of our products are chosen with provider and veteran care in mind.

Orders can be placed by contacting our team directly via phone at 702-525-9981 or emailing us at admin@semperfimedical.com. Online ordering will be available soon!

Yes. We work closely with provider offices and care teams to support patients eligible through Medicare, private insurance, and VA Community Care referrals.
Most in-stock products ship within 2–3 business days. We offer standard and expedited shipping nationwide. Local deliveries in the Las Vegas area may be eligible for same-day drop-off.

Reach out to us anytime at admin@semperfimedical.com or call 702-525-9981. We’re available Monday–Friday, 9 AM to 5 PM PT.

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